Derek Thompson: Steve, I want to start with you: VO2 max. If you’re a listener who is anywhere proximate to the health and lifespan world, there is a 90 percent chance you have heard the term “VO2 max” in the last year, maybe the last month, possibly the last 15 minutes. This is a health and fitness metric that seems to have exploded into popular consciousness in large part thanks to the bestselling book Outlive by Peter Attia. The New York Times just recently, last week, called VO2 max “the best way to track fitness and longevity.” The best way to track fitness and longevity. Steve, ground-floor level please, what is VO2 max?
Steve Magness: I’ve got to say, as an exercise scientist, it humbles me that this has now come out as the thing when we’ve been able to measure VO2 max since about the 1930s. But anyways, what is VO2 max? Quite simply, it’s the maximum amount of oxygen that we can utilize. So it’s essentially how much oxygen you can breathe in, and then go through your circulatory system, and then utilized by the muscles, and that’s what it is. So the way we measure it is pretty simple. You get put on a treadmill or a bike in an exercise science or a doctor’s lab. They hook you up to a mask. That mask has a tube that runs into a machine or a bag that essentially measures how much oxygen you’re breathing in and out, and then they ramp up the exercise. You start really easy, and then the speed gets faster on the treadmill every one or two minutes, depending on the protocol.
And you keep that going until essentially you cry uncle, which is you are so exhausted that you either fall off the back of the treadmill, which happens with elite athletes, or, more so with regular people, you just scream, hit stop, and just are done. And generally, at the end of the fastest that you’re going on that treadmill, your oxygen consumption is at its highest level, and whatever that number is is your VO2 max. And it’s a surrogate indicator of cardiovascular or aerobic fitness. And the way I like to describe it is it’s the measure of the engine size of the car. So it’s that big number that we use holistically to look at aerobic fitness.
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Magness: They use the speed that you reached at the end of the treadmill when you called uncle, when you quit. So I think this is really important because we confuse the thing. We say, “Oh. It’s VO2 max. It’s VO2 max. It’s VO2 max.” Vast majority of times in these mortality longevity studies, it’s not. We use that speed, or incline, or watts on the bike, and say, essentially, “How fast can you get until you’re exhausted on this test?” And that is what correlates to mortality, longevity, etc.
Health Fads and Fictions: VO2 Max, Supplement Mania, Sunlight, and Immortality